Idria G

IDRIA pure or monocyte-rich PRP product contains IDRIA G tube and accessories for blood draw. IDRIA G can offer pure PRP in plasma with partial presence of white cells and a complete depletion of red blood cells. This clean solution is an important prerogative for all clinical application. Gel separation, during the centrifugation allows separation of blood components according to their density concentrating platelets and separating them from the inflammatory component of white blood cells. Platelets precipitate on the top part of the gel, while granulocytes and red blood cells are trapped under the gel at the bottom of the tube. The use of anticoagulant M-ACD-7 (Citric acid trisodium dihydrate salt) controls and maintains the natural pH ideal for tissue regeneration. 

IDRIA G provides a powerful concentration of deliverable regenerative cells without catabolic contaminants. By recovering platelets and monocytes (depending on the protocol), it exerts a synergistic action that modulates the response of the surrounding cells in the lesion or injection area, facilitating rapid tissue healing. 

By processing 28 ml of blood, physicians can obtain 4 ml of PRP and 8 ml of PPP with high concentrations of regenerative cells in a single 8-minute spin (1500 rgf). The specially designed separating gel optimizes the biological profile of the obtained PRP by ensuring: 

• High yield of platelets and mononucleated cells;
• Complete depletion of pro-inflammatory cells (red blood cells and granulocytes) with no presence of catabolic elements;
• High concentration of anabolic cytokines; 

IDRIA G induces proliferation and differentiation of various cell types, enhancing the production of collagen, elastin, and proteoglycans, stimulating angiogenesis and chemotaxis, inhibiting metalloproteinases, and polarizing macrophages from the inflammatory M1 phase to the regenerative M2 phase.