Introducing Monocyte-rich PRP from IDRIA M - the ultimate solution for clinical applications
Monocyte-rich PRP contains the IDRIA M 28ml tube and accessories for blood draw. IDRIA M facilitates the production of PRP in plasma, enriching it with monocytes and lymphocytes while completely depleting granulocytes and red blood cells. This pristine solution is crucial for various clinical applications. During centrifugation, the gel separation technique efficiently separates blood components based on density. Concentrating platelets and mononuclear cells while isolating them from the inflammatory component of white blood cells. Platelets and monocytes precipitate in the upper portion of the gel. While red blood cells and granulated cells are trapped beneath it at the tube’s bottom. The use of the M-ACD-7 anticoagulant (Citric acid trisodium dihydrate salt) helps control and maintain the ideal pH for natural tissue regeneration.
IDRIA M provides a powerful concentration of deliverable regenerative cells without catabolic contaminants. By recovering platelets and monocytes, it exerts a synergistic action that modulates the response of the surrounding cells in the lesion or injection area, facilitating rapid tissue healing.
By processing 28 ml of blood, physicians can obtain 4 ml of PRP and 8 ml of PPP with high concentrations of regenerative cells in a single 8-minute spin (1500 rgf). The specially designed separating gel optimizes the biological profile of the obtained PRP by ensuring:
- High yield of platelets and mononucleated cells;
- Complete depletion of pro-inflammatory cells (red blood cells and granulocytes) with no presence of catabolic elements;
- High concentration of anabolic cytokines;
IDRIA M induces proliferation and differentiation of various cell types, enhancing the production of collagen, elastin, and proteoglycans. Stimulating angiogenesis and chemotaxis, inhibiting metalloproteinases, and polarizing macrophages from the inflammatory M1 phase to the regenerative M2 phase.
Red Cells: Less than 0,03%. Granulocytes: Less then 0,2%
Dedicated Gel Separator: Optimizes cells concentration and eliminates inflammatory factors
Recovery: Platelets: 89% Mononucleated Cells: 78%
Closed system: Ensures complete safety throughout the entire processing
Monocyte-rich PRP (M-PRP) is a specific subtype of platelet-rich plasma (PRP) that contains a higher concentration of monocytes, a type of white blood cell involved in the immune response and tissue repair processes. While M-PRP is not as widely studied as traditional PRP, its increased concentration of monocytes may offer additional benefits in certain applications due to their role in promoting tissue regeneration, angiogenesis, and anti-inflammatory effects. Potential areas where Monocyte-rich PRP could be applied include: